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Lionel Chow, M.D., Ph.D.
Wright State University & Dayton Children's Hospital
2011 Sontag Award Recipient
"The Sontag Foundation provides direct mentorship, exposure, and access to a cadre of senior and peer mentors that is unattainable in any other setting. I am forever grateful for the opportunities and encouragement the Foundation has provided me throughout my career."
About DSA-Funded Research
Dr. Chow's research program focuses on developing unique patient-derived xenograft models of pediatric brain tumors in order to advance novel treatments for high-grade tumors. His lab has developed a novel laboratory mouse model that closely resembles the human disease at both the microscopic and genetic levels. By studying the tumors that arise in these animals rigorously and comparing them to tumors obtained from both adult and pediatric patients, they will learn more about the genes and proteins that have been altered leading to glioblastoma growth and survival. This may also lead to the goal of finding new drug targets and/or drug combinations that have a high chance of success and that will be tested in patients with glioblastoma.
Associate Professor of Pediatrics, Hematology/Oncology, Wright State University