Hello, you are using an old browser that's unsafe and no longer supported. Please consider
your browser to a newer version, or downloading a
Cheng-Yu Lee, Ph.D.
University of Michigan
2008 Sontag Award Recipient
"Thank you for believing in me. The Foundation's generosity and dedication inspire me to work hard everyday to contribute to brain cancer research."
About DSA-Funded Research
Stem cells are progenitors that maintain stemness (self-renewal) while generating diverse differentiated cell types. Thus, a stem cell's decision to self-renew or to differentiate has profound consequences in development, homeostasis and regeneration. Recently, the role of cancer stem cells in several types of malignancies has been demonstrated; many parallels exist between normal and cancer stem cells — specifically, their ability to self-renew extensively and to generate a wide variety of differentiated cell types. Thus, elucidation of the molecular mechanisms leading to self-renewal or to differentiation is beneficial for both stem cell and cancer biology. The Lee Lab uses Drosophila neural stem cells as a model to study regulation of self-renewal versus differentiation.
Robert H Bartlett Collegiate Professor of the Life Sciences, University of Michigan
Research Associate Professor, U-M Life Sciences Institute, University of Michigan
Associate Professor, Internal Medicine and Cell and Developmental Biology, U-M Medical School