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2008 Sontag Award Recipient

"Thank you for believing in me. The Foundation's generosity and dedication inspire me to work hard everyday to contribute to brain cancer research."

About DSA-Funded Research

Stem cells are progenitors that maintain stemness (self-renewal) while generating diverse differentiated cell types. Thus, a stem cell's decision to self-renew or to differentiate has profound consequences in development, homeostasis and regeneration. Recently, the role of cancer stem cells in several types of malignancies has been demonstrated; many parallels exist between normal and cancer stem cells — specifically, their ability to self-renew extensively and to generate a wide variety of differentiated cell types. Thus, elucidation of the molecular mechanisms leading to self-renewal or to differentiation is beneficial for both stem cell and cancer biology. The Lee Lab uses Drosophila neural stem cells as a model to study regulation of self-renewal versus differentiation.

Current Appointment(s)
  • Robert H Bartlett Collegiate Professor of the Life Sciences, University of Michigan
  • Research Associate Professor, U-M Life Sciences Institute, University of Michigan
  • Associate Professor, Internal Medicine and Cell and Developmental Biology, U-M Medical School
  • University of Maryland, B.S., Biology
  • University of Maryland, Ph.D., Biology
  • University of Oregon, Postdoctoral Fellow