"For nearly forty years, we have recognized the tremendous capacity for glioblastoma to not simply evade, but to systematically hunt down and damage patient T cells, which might otherwise foster anti-tumor immunity. The Sontag Foundation provides a unique environment of diverse researchers with the ability to truly make an impact on this deadly disease. It is an honor to be part of this community."

About DSA-Funded Research

Dr. Fecci's Lab focuses on understanding and reversing T cell dysfunction in patients with glioblastoma (GBM) and brain metastases. They employ a systematic approach to categorizing T cell dysfunction and heavily study T cell ignorance and exhaustion. They focus on combining strategies for reversing T cell deficits with current and novel immune-based platforms as a means of deriving and improving rational and precise anti-tumor therapies.